eLife

Compensation of hyperexcitability with simulation-based inference

Simulation-based inference predicts putative circuit mechanisms of hyperexcitability in a phenomenological microcircuit ...
Science

Graph-based pangenome analysis uncovers structural and functional impacts of allopolyploidization events

The emergence of graph pangenomes has advanced the study of structural variants (SVs) across diverse species, yet the impact of complex ploidy on SV landscapes remains poorly explored. Brettanomyces ...
BIOENGINEER

AI Model Scores College Spoken English With 95 Percent Accuracy

A new open-access study reports an AI and IoT-based system that classifies college spoken English performance with 95.47 ...
xenospectrum

ScholarEvolve Lets AI Agents Rewrite Their Own Code From Research Papers, Lifting Task Completion 12.4 Points

UCSB and Microsoft's ScholarEvolve generates code from academic papers to improve an agent's harness without retraining model ...
kucoin

MIT researchers use GPT-6 Astra to enhance Qwen's mathematical ability by 6x

Article by Shenchao TechFlowNo training required, no data needed, no gradient descent.Researchers at MIT fed the weights of ...
eLife

Connectomic Analysis of Mitochondria in the Central Brain of Drosophila

This study provides a valuable resource describing the size, density, and synaptic proximity of mitochondria across thousands of neurons in the Drosophila brain, drawn from a well-annotated electron ...
Science

Cas9 nickase–mediated contraction of CAG/CTG repeats is associated with phenotypic improvements in a Huntington’s disease mouse model

Cas9 nickase contracts CAG/CTG repeats in Huntington’s disease patient–derived medium spiny neurons and in a mouse disease model.